Ipamorelin, 2mg

Ipamorelin, 2mg

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Ipamorelin, also called as NNC 26-0161, is a pentapeptide, Ghrelin receptor agonist and selective secretagogue of growth hormones. The short chain peptide contains 5 amino acids with long half-life. Ipamorelin demonstrated significant growth hormone releasing capability in experimental studies including in vivo and in vitro. The action of Ipamorelin mimics GHRP-6, promotes growth hormone release from the pituitary cells by acting on GHRP-like receptors. Studies suggest that the compound did not influence cortisol or ACTH levels. Ipamorelin is being studied extensively by the biomedical researchers due to high specificity. The molecular weight and formula of Ipamorelin is 711.85 and C38H49N9O5. Just like GHRP-2 and GHRP-6, ipamorelin suppresses the action of somatostatin and stimulate the production and secretion of GH. Ipamorelin the third generation of the GHRPs , however it is more enhanced than its predecessors and has a longer half life.

Research indicates that ipamorelin mainly acts by activating specific G-protein secretagogues, which in turn increases gastric emptying and gastric motility. The major target for the hormone is the anterior lobe of the pituitary gland where it induces the release of growth hormone, recent studies shows that the hormone has no effect on the level of luteinizing hormone, PRL, follicle stimulating hormone and thyroid stimulating hormone. The GRLN receptor is responsible for the activation of tiny molecules on the pituitary gland, which in turn brings the release of growth hormone. Ipamorelin is known to act on the same receptor that GH acts on, however somatostatin hinders the production and secretion of GH since they are produced in pulses. An increase in the concentration of the polypeptide allows the hormone to be produced in a continuous flow and therefore inducing cell division, proliferation, differentiation, development and maturity thereby bringing about growth and development. D-Lys3-GHRP-6 is the only antagonist to the hormone since it denatures receptor sites therefore the hormone cannot bind to the desired ligand.

Ipamorelin Chemical Profile

CAS: 170851-70-4
Formula: C38H49N9O5
Molecular weight: 711.86
Peptide purity: > 99.0%
Chain: Aib-His-D-2-Nal-D-Phe-Lys-NH2



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